Rethinking of back pain remedies

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Why conventional back pain remedies may need a rethink

Back pain and discomfort can be debilitating, with millions of people suffering from it around the world. Traditionally, treatment options have included everything from drugs to surgical procedures. But new studies suggest that some of these commonly prescribed treatments could be less effective than believed, leading to a re-evaluation of existing medical treatments.

Spinal cord stimulation 

SCS,consists of an implanted device that sends electrical impulses to the spinal cord to interrupt pain signals before they reach the brain. This has been a preferred strategy for patients with chronic back pain who have had no response to other therapies. But a review of 13 clinical trials that included 699 participants, conducted by Cochrane, found SCS is not associated with statistically significant long-term relief from low back pain compared with placebo. Also, risk factors from the procedure, such as nerve injury, infection, and the failure of the implanted device, raise questions about the widespread use of this device.

The role Opioids in managing pain

Opioids have been frequently prescribed for acute back and neck pain. A study led by the University of Sydney found that opioids are no better than placebo for acute back and neck pain. In addition, patients who received opioids were at higher risk for misuse in the next 12 months, even with a relatively short treatment course. These results suggest that current recommendations to use opioids only when all other options have been exhausted should be reconsidered, based not only on the lack of benefit but also the potential for harm.

How Back Pain Might Develop After a Time

The potential long-term impact of back pain was the focus of a study by the University of South Australia, which found that while most people recover well from back pain in the first six months of suffering from it, long-lasting pain, beyond three months, is less likely to allow one to recover fully. Thus, persistence of pain is often attributed to hypersensitivity of the pain system vs. actual tissue damage and justifying the use of the treatment strategies that address the physical and neurological mechanisms driving pain.

Approach to target Senescent Cells  

There’s also the potential to identify and target senescent cells (cells that have stopped dividing), which could help address back pain, with new research suggesting senescent cells (cells that are aging or damaged) play a role as they build up in tissue and are thought to contribute to many chronic diseases, in addition to problems associated with back pain. In a separate study in eLife, scientists found that the drug Navitoclax, which targets these dormant cells, dramatically lowered spinal pain and degeneration in mice by killing off senescent osteoclasts. It’s promising but needs to be tested in humans in more clinical trials.

Implication as a Future Treatment Strategy

These findings point to a necessity for a paradigm change in back pain management. Here are a few key considerations:
Non-Invasive Therapies: Physical as well as psychological or emotional therapies may treat the physical aspect of, but also the mental aspect of, pain, which may be set to treatment with longer-lasting effects.
Teaching patients: Educating the patients about chronic pain itself and that many treatments have limited goals can prepare them to have more realistic expectations and make better choices.
Individualized Treatment Plans: Knowing that back pain has many causes and a variety of therapies tailored to the individual patient and condition may be required.
Exploration Ahead: More work needs to be done to understand how the mechanisms of back pain work and to develop new treatment options.

Conclusion: The evolving understanding of back pain and its redress illustrates the need for evidence-based medicine. As new discoveries peel back the layers of performance enhancement of prevalent strategies often utilized to address spinal inflammation,including spinal cord stimulation procedures and opioid prescriptions,all care providers and patients should be proactive about recognizing alternatives that prioritize safety, efficacy, and holistic well-being.

Thanks for reading, 

Have a nice day 😊. 


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